Ectrodactyly-ectodermal dysplasia-clefting (EEC) syndrome.

The Ectrodactyly-Ectodermal Dysplasia-Clefting syndrome is also known as the EEC syndrome. The word ectrodactyly is derived from the Greek, and means congenital absence of all or part of a finger or toe. While both hands and both feet are usually involved, exceptions have been noted in that one hand may be normal and, rarely, all extremities are normal. Tear ducts are abnormal in most affected individuals; as a result, excessive tearing, inflammation of the eyelids, cornea, and conjunctiva, and sensitivity to light (photophobia) may occur. Skin and hair may be more lightly pigmented than normal and scalp hair, eyebrows, and eyelashes are sparse. Nails in some, but not all, people with the disorder may be abnormal.